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. 2016 Jul 18;2016:4970858. doi: 10.1155/2016/4970858

Table 1.

Comparison between six other cases of MI associated with steroid use.

Case Ferenchick and Adelman [14] Yildirim et al. [15] Arslan et al.
[16]
Takamatsu et al. [17] Owecki and Sowiński [18] Poorzand et al. [2]
Age (years) 37 64 20 79 66 23

Risk factors Family history of CAD HLD Smoking
(7 years)
Bortezomib use Smoking
HLD

Gender Male Male Male Female Female Male

Steroid type Nandrolone-decanoate,
Boldenone,
testosterone-cypionate,
Stanozolol,
and veterinary
oxandrolone
Prednisolone Methylprednisolone Dexamethasone Methylprednisolone Dexamethasone

Indication Anabolic steroids (weightlifting) Idiopathic intracranial HTN
(papilledema)
Anaphylaxis Multiple
myeloma
Graves Anabolic steroids
(wrestling)

Route Intramuscular & oral Oral Intravenous Intravenous Intravenous Intramuscular

Dose 200 mg/week for 16 weeks
1.5 cc q3 days/16 weeks
1.5 cc q4 days/16 weeks
1.5 cc q3 days/16 weeks
50 mg daily for 16 weeks
40 mg
daily
40 mg NA 1 gm daily NA

Duration of use Intermittent for 7 years
and then 16 weeks before the event
One month 7 minutes 5 days 5 days 6 months

Possible confounders Hypotension secondary to anaphylaxis Bortezomib use

Acute coronary syndrome type STEMI NSTEMI and then STEMI few days later STEMI STEMI NSTEMI STEMI

EKG ST elevation,
II, III, and aVF
ST elevation, II, III, and aVF;
ST depression,
I, aVL
ST elevation,
I, aVL
ST elevation,
aVR;
ST depression,
I, II, and aVF
V2–6
NA ST elevation,
I, aVL

Echo Normal Normal EF 35% apical & posterolateral wall motion abnormality EF 68%
posterior &
anterolateral akinesia
Anteroseptal akinesia EF 35%
apical, midanterior, anteroseptal
akinesia

Left heart catheterization findings Normal coronaries
(3 days following tissue plasminogen activator)
RCA: slow flow
and then PDA total occlusion
& LAD slow flow
Normal coronaries 10 days later
(normal IVUS)
(treated with Aspirin & Heparin)
LM/LCX significant lesions LAD mod stenosis LAD total occlusion RCA critical stenosis Nonobstructive CAD (4 days after streptokinase)

Complications LV thrombus