Table 1.
Group | Sample size | TSLP | IL-4 | IL-5 | IL-13 |
---|---|---|---|---|---|
Control group | 20 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 |
VKC group | 20 | 48.91 ± 7.45 | 14.06 ± 3.50 | 10.88 ± 1.82 | 34.28 ± 8.42 |
SAC group | 20 | 24.63 ± 2.43 | 7.71 ± 0.65 | 5.10 ± 1.33 | 23.77 ± 6.29 |
PAC group | 20 | 21.56 ± 2.72 | 3.30 ± 1.50 | 2.43 ± 1.28 | 17.67 ± 4.28 |
F | 349.71 | 200.29 | 260.49 | 128.23 | |
P | <0.001 | <0.001 | <0.001 | <0.001 |
TSLP, IL-4, IL-5, and IL-13 concentrations in the control group were not detected, but these were detected in VKC, SAC, and PAC patient specimens. The results of the four different types of allergic conjunctivitis are shown as mean ± SD. The Luminex microbead assay confirmed that the patient groups had different degrees of the increase in concentration of the cytokines compared with the normal control group. P < 0.001; each group n = 20.
VKC: vernal keratoconjunctivitis; SAC: seasonal allergic conjunctivitis; PAC: perennial allergic conjunctivitis.