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. 2016 Feb 25;594(15):4119–4129. doi: 10.1113/JP270963

Figure 2. Hydrogen sulfide synthesis and effector ion channels .

Figure 2

Schematic diagram illustrating the synthesis of H2S from homocysteine, l‐ and d‐cysteine via enzymes shown in boxes (CBS, cystathionine β synthase; CSE, cystathionine γ lyase; 3‐MST, 3‐mercaptopyruvate sulfurtransferase; CAT, cysteine aminotransferase; DAO, d‐amino acid oxidase). Some of the target ion channels modulated by H2S are also indicated (NMDAR, N‐methyl‐ d‐aspartate receptor; KATP, ATP‐sensitive K+ channel; BKCa, large conductance K+ channel; VGCC, voltage‐gated Ca2+ channel; TRP, transient receptor potential channel).