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. 2016 Jul 20;6(7):160101. doi: 10.1098/rsob.160101

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© 2016 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 5. — A single intraperitoneal injection of immunogenic particles induces a remodelling of the heart architecture. (a–c) Representative sections of hearts labelled with Phalloidin, a muscle marker, at 30 dpi. Dashed lines separate compact and trabecular myocardium. (d–f) Morphometric measurements of hearts at 30 dpi. No difference in heart size was noted (d), but a thickening of the compact myocardium was observed in fish injected with either LPS or Zymosan. (f) The density of CMs (number of CMs per 10 000 µm² of cardiac muscle) was higher at 30 dpi in the compact myocardium of LPS- or Zymosan-injected fish (n ≥ 4 hearts; ≥2 sections per heart; n.s., non-significant; *p < 0.05; ***p < 0.001).