Signaling events mediated by HDAC Class III |
CDKN1A, HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4, TP53 |
6.22E-18 |
Glucocorticoid receptor regulatory network |
AKT1, CDKN1A, IFNG, IL4, IL6, IL8, KRT14, KRT17, KRT5, SFN, STAT1, TP53 |
6.73E-08 |
VEGFR1 specific signals |
AKT1, CALM1, CALM2, CALM3, NOS3, RASA1, VEGFA |
1.52E-06 |
AP-1 transcription factor network |
BAG1, CCL2, IFNG, IL10, IL4, IL6, IL8, MMP9, TP53 |
9.53E-06 |
Caspase Cascade in Apoptosis |
AKT1, APAF1, ARHGDIB, GSN, RIPK1, TNF, VIM, XIAP |
1.43E-05 |
Insulin-mediated glucose transport |
AKT1, CALM1, CALM2, CALM3, SFN, YWHAZ |
1.84E-05 |
SHP2 signaling |
EGF, EGFR, IFNG, IL6, LCK, NOS3, STAT1, VEGFA |
1.85E-05 |
a6b1 and a6b4 Integrin signaling |
AKT1, CDH1, EGF, EGFR, ERBB2, SFN, YWHAZ |
2.94E-05 |
Angiopoietin receptor Tie2-mediated signaling |
AKT1, CDKN1A, FGF2, FYN, NOS3, RASA1, TNF |
4.45E-05 |
ErbB1 downstream signaling |
AKT1, CALM1, CALM2, CALM3, EGF, EGFR, RALA, SFN, STAT1, YWHAZ |
5.51E-05 |
IFN-gamma pathway |
AKT1, CALM1, CALM2, CALM3, IFNG, STAT1 |
1.80E-04 |
ErbB receptor signaling network |
EGF, EGFR, ERBB2, TGFA |
2.31E-04 |
HIF-1-alpha transcription factor network |
AKT1, ALDOA, ENO1, PGK1, PKM, TF, VEGFA |
3.18E-04 |
Calcium signaling in the CD4+ TCR pathway |
CALM1, CALM2, CALM3, IFNG, IL4 |
3.20E-04 |
LKB1 signaling events |
CTSD, EZR, MAPT, SFN, TP53, YWHAZ |
3.29E-04 |
Ceramide signaling pathway |
AKT1, CTSD, EGF, EIF2AK2, RIPK1, TNF |
3.68E-04 |
Direct p53 effectors |
APAF1, CDKN1A, CTSD, EGFR, HSPA1A, HSPA1B, PCNA, SFN, TGFA, TP53 |
3.82E-04 |
Signaling events mediated by PTP1B |
AKT1, EGF, EGFR, FYN, LCK, TXN |
5.05E-04 |
Signaling events mediated by VEGFR1 and VEGFR2 |
AKT1, CALM1, CALM2, CALM3, FYN, NOS3, VEGFA |
5.30E-04 |
EGF receptor (ErbB1) signaling pathway |
EGF, EGFR, GSN, RASA1, STAT1 |
5.66E-04 |