Figure EV4. Effect of starvation and exogenous HA‐HuR expression on lung HuR and miRNA levels in BALB/c.
- Scheme of the starvation experiment is shown.
- Effect of starvation on lung HuR and let‐7a miRNA levels in the lungs of Starved animals determined by Western blot and qRT–PCR, respectively. Mean C t values for RNA samples isolated from the lungs of Fed and Starved animals were shown (mean ± s.e.m., n = 4). β‐Actin was used as loading control in HuR Western blot.
- Scheme of the experiment where HA‐HuR expression or control (pCIneo) plasmids were injected via tail vein.
- Effect of HA‐HuR expression plasmid injection on lung HuR level in mouse (mean ± s.e.m., n = 3). Western blot was done on lung lysates obtained from control or HA‐HuR plasmid‐injected animals. β‐Actin was used as loading control. Relative levels of let‐7a miRNA are represented as mean C t values for the same amount of lung RNA used.