Table 5.
Global Deficit Scores (GDS)
| Treatment | 0 Min | 60 Min 2 Puffs |
120 Min 3 Puffs |
180 Min 4 Puffs |
240 Min | 300 Min | |
|---|---|---|---|---|---|---|---|
| Pegs Dom | 7% | 1.3 | 1.5 | 2.0 | 2.0 | 2.0 | 1.7 |
| 3.5% | 1.3 | 1.5 | 1.4 | 1.8 | 1.7 | 1.3 | |
| Placebo | 1.8 | 1.4 | 1.2 | 1.4 | 1.6 | 1.3 | |
| Pegs | 7% | 1.2 | 1.4 | 1.5 | 2.0 | 1.9 | 1.7 |
| Nondom | 3.5% | 1.1 | 1.3 | 1.4 | 1.5 | 1.5 | 1.3 |
| Placebo | 1.4 | 1.4 | 1.2 | 1.4 | 1.3 | 1.1 | |
| Digit Symbol | 7% | 0.9 | 0.9 | 0.9 | 1.1 | 1.3 | 0.8 |
| 3.5% | 0.6 | 0.8 | 0.9 | 0.7 | 0.7 | 0.5 | |
| Placebo | 0.8 | 0.6 | 0.5 | 0.5 | 0.5 | 0.5 | |
| HVLT–Learn | 7% | 1.2 | 2.2 | 2.4 | 2.8 | 3.3 | 2.9 |
| 3.5% | 1.1 | 1.9 | 2.2 | 2.7 | 2.9 | 2.7 | |
| Placebo | 1.2 | 1.6 | 1.3 | 1.6 | 2.1 | 1.7 | |
| HVLT–Delay | 7% | 1.5 | 2.8 | 3.3 | 3.7 | 4.2 | 3.8 |
| 3.5% | 1.6 | 2.3 | 3.1 | 3.4 | 3.9 | 3.5 | |
| Placebo | 1.5 | 2.5 | 2.6 | 2.5 | 3.5 | 3.3 | |
| Average GDS |
7% | 1.2 | 1.8 | 2.0 | 2.3 | 2.5 | 2.2 |
| 3.5% | 1.1 | 1.5 | 1.8 | 2.0 | 2.2 | 1.8 | |
| Placebo | 1.3 | 1.5 | 1.4 | 1.5 | 1.8 | 1.6 |
Abbreviation: HVLT, Hopkins Verbal Learning Test Revised.
NOTE. Significant results (P< .05) are bolded.
Categorization of each raw deficit score was performed using clinically relevant cutoff points.
T ≥ 40 (deficit score (DS = 0; no impairment), 35 ≤ T ≤ 39 (DS = 1; mild impairment), 30 ≤ T ≤ 34 (DS = 2; mild-to-moderate impairment), 25 ≤ T ≤ 29 (DS = 3; moderate impairment), 20 ≤ T ≤ 24 (DS = 4; moderate-to-severe impairment), T < 20 (DS = 5; severe impairment).