Table 1.
Summary of results indicating neuroendocrine and behavioral changes seen in adolescent and adult female rats following exposure to chronic stress during the late adolescent period
| Adolescent | Adult | |
|---|---|---|
| Behavior | ||
| Immobility | − | ↑ |
| HPA axis | ||
| CORT baseline | ↑ | − |
| CORT stress-induced | − | ↓ |
| ACTH stressed-induced | ↓ | ↓ |
| Neuropeptide mRNA expression | ||
| PVN | ||
| CRH | ↑ | − |
| GR | − | ↓ |
| dpPVN | ||
| OXT | ↓ | − |
| AVP | ↑ | − |
| mpPVN | ||
| AVP | − | ↓ |
| mPVN | ||
| OXT | − | ↑ |
| AVP | ↑ | − |
| Somatic | ||
| Body Weight | ↓ | ↓ |
| Thymus | − | ↑ |
| Adrenal glands | − | ↑ |
Up arrows indicate significant increase in response to adolescent stress exposure relative to age matched non-stressed controls.