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Comparison between mAbs 2H4 and FI6.5 Abbreviations: SHM, somatic hypermutation; nt, nucleotide; aa, amino acid.
| Heavy chain |
Light chain |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| V gene | CDR3 length (aa) | N1 nt | D gene | N2 nt | J gene | SHM nt (aa) | V gene | CDR3 length (aa) | N nt | J gene | SHM nt (aa) | |
| 2H4 | 3–48*03 | 18 | 2 | 3–22*01 | 31 | 4*02 | 23 (13) | K1–39*01 | 9 | 0 | 2*01 | 15 (7) |
| FI6 | 3–30*18 | 20 | 22 | 3–9*01 | 11 | 4*02 | 26 (17) | K4–1*01 | 9 | 0 | 1*01 | 14+6 (9+2) |
