Table 1.

Kinetic constants used for modeling that are taken from Mazor et al.⁶ or derived.

	CD4				CD70
DuetMab	k1×105 1/(M s)	k−1×10−3 1/s	t−1½ s	1k−4×10−3 1/s	k2 ×105 1/M s)	k−2×10−3 1/s	t½s	k3×1013 dm2/(mol s)
parent	2.8	0.26	2665	0.19	2.0	4.9	141	2.4
VkY92A	2.0	1.9	365	1.9	2.0	4.9	141	2.4
VkY91A	2.8	4.7	147	3.3	2.0	4.9	141	2.4
VkR95A	5.4	23	30	8.5	2.0	4.9	141	2.4
VkR95A+VhD97A	5.6	35	20	12.5	2.0	4.9	141	2.4
VkR94A+VhY99A	5.2	36	19	13.8	2.0	4.9	141	2.4

¹Calculated according to Equation 10.