Skip to main content
. 2016 Aug;6(8):a026039. doi: 10.1101/cshperspect.a026039

Table 1.

p53 isoform-specific small interfering RNAs (siRNAs)

Position on sequence (nt) GenBank accession number (NG_017013) Exon location Exon sequence Targeted forms
si E2 15968–15986 Exon 2 GCAGUCAGAUCCUAGCGUC p53α, p53β, p53γ,
Δ40p53α, Δ40p53β,
Δ40p53γ
si 133a 17212–17230 Intron 4 GGAGGUGCUUACACAUGUU Δ133p53α, Δ133p53β,
Δ133p53γ, Δ160p53α,
Δ160p53β, Δ160p53γ
si 133b 17271–17289 Intron 4 CUUGUGCCCUGACUUUCAA Δ133p53α, Δ133p53β,
Δ133p53γ, Δ160p53α,
Δ160p53β, Δ160p53γ
si E7 18322–18340 Exon 7 GCAUGAACCGGAGGCCCAU All
si E7/E8 18363–18370/
18714–18724
Exon 7 and 8 GACTCCAGTGGTAATCTAC All
si β 19211–19229 Exon 9β GGACCAGACCAGCUUUCAA p53β, Δ40p53β,
Δ133p53β, Δ160p53β
si γ 19009–19016/
19285–19295
Exon 9 and 9γ CCCUUCAGAUGCUACUUGA p53γ, Δ40p53γ,
Δ133p53γ, Δ160p53γ
si Splice 19284–19302 Exon 9β and 9γ GAUGCUACUUGACUUACGA p53β, Δ40p53β,
Δ133p53β, Δ160p53β,
p53γ, Δ40p53γ, Δ
133p53γ, Δ160p53γ
si α 21846–21864 Exon 10 GUGAGCGCUUCGAGAUGUU p53α, Δ40p53α,
Δ133p53α, Δ160p53α