FIG. 4.

Biomarker concentrations. Ubiquitin carboxyl-terminal hydrolase -L1 (UCH-L1) and GFAP concentrations in microdialysate (A,B) and in serum (C,D). In early phase of reperfusion UCH-L1 MD concentration in normothermia group was highest and significantly higher than sham rat group ( *; p<0.01). Also, UCH-L1 MD in early hypothermia group was significantly lower than normothermia group ( #; p<0.01). GFAP concentration in normothermia was highest and peaked in the late phase of reperfusion (**; p<0.05 vs sham). The differences between means of serum values were not significantly different.

Abbreviations; E-Hypo; early hypothermia group, L-Hypo; late hypothermia group, Normo; normothermia group.