Fig. 6.

TTC (2,3,5-triphenyltetrazolium chloride) volumetry in each treatment group

(A) An examples of TTC injury area in each treatment group, 6mm from the tip (±1.0 mm from bregma). In TTC staining, ischemic injuries were identified with unstained, white areas (asterisk). In sham rat, we could not find any ischemia in these pictures. On the other hand, in late induced hypothermia and normothermia group, we could identify large ischemic lesions compared to early hypothermia group. (scale bars = 5mm ) Abbreviation, E-Hypo; early induced hypothermia group, L-Hypo; late induced hypothermia group, Normo; normothermia group,

(B) Ischemic area in each sections (Mean±SEM). In early induced hypothermia group, injury volume was smaller across all sections.

(C) Ischemic volume. In early- hypothermia group, ischemic area was significantly smaller than late hypothermia and normothermia group (*p<0.05).

Abbreviation, E-Hypo; early induced hypothermia group, L-Hypo; late induced hypothermia group, Normo; normothermia group.