TABLE 1.
Physiologic variables in experimental time course (Mean±SEM).
| 0.5 hr before ASDH induction |
1 hr after ASDH induction |
2 hr after ASDH induction (0.5 hr after craniotomy) |
4 hr after ASDH induction (1.5 hr after craniotomy) |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Normo | Early | Late | Sham | Normo | Early | Late | Sham | Normo | Early | Late | Sham | Normo | Early | Late | Sham | |
| Mean Arterial Pressure (mmHg) | 116.8 ± 20.5 | 112.5 ± 18.3 | 119.5 ± 17.4 | 116.8 ± 20.5 | 110.7 ± 14.8 | 116.0 ± 18.8 | 116.4 ± 14.9 | 109.8 ± 9.7 | 116.5 ± 12.6 | 112.8 ± 13.5 | 116.4 ± 13.3 | 109.6 ± 8.2 | 105.2 ± 13.7 | 116.5 ± 12.1 | 110.9 ± 16.6 | 109.3 ± 9.2 |
| pH | 7.463 ± 0.062 | 7.459 ± 0.034 | 7.467 ± 0.033 | 7.500 ± 0.046 | 7.484 ± 0.035 | 7.454 ± 0.032 | 7.456 ± 0.050 | 7.484 ± 0.035 | 7.459 ± 0.029 | 7.454 ± 0.028 | 7.433 ± 0.067 | 7.459 ± 0.029 | 7.432 ± 0.041 | 7.401 ± 0.050 | 7.388 ± 0.043 | 7.442 ± O.039 |
| PaO2 (mmHg) | 103.1 ± 15.8 | 100.8 ± 12.5 | 122.9 ± 34.7 | 97.4 ± 12.6 | 125.6 ± 16.9 | 117.9 ± 14.8 | 129.1 ± 22.8 | 125.6 ± 16.9 | 128.1 ± 26.8 | 122.9 ± 13.7 | 123.2 ± 29.2 | 128.1 ± 26.8 | 137.4 ± 26.9 | 130.2 ± 18.5 | 146.8 ± 32.4 | 137.4 ± 26.9 |
| PaCO2 (mmHg) | 35.5 ± 2.5 | 36.7 ± 2.9 | 36.3 ± 4.2 | 34.0 ± 4.0 | 33.5 ± 3.5 | 34.4 ± 4.1 | 33.7 ± 4.7 | 32.7 ± 4.3 | 33.7 ± 1.5 | 33.0 ± 2.2 | 35.9 ± 4.9 | 32.4 ± 3.3 | 34.1 ± 3.1 | 34.3 ± 2.3 | 34.5 ± 2.9 | 34.1 ± 3.1 |
Abbreviations: Normo; normothermia group, Early; early hypothermia group, Late; late hypothermia group, Sham; sham-operated group, ASDH; acute subdural hematoma.