Table 1.

t₅₀ (in hours) Values of Fibril Formation Kinetics of AL Proteins at pH 2.0

	AL-09	AL-103	AL-12	κI	AL-T05
de novo (pH 7.4)	244.1 ± 14.2a	172.1 ± 36.7b	430.0 ± 20.0c	−	15.8 ± 0.9d
de novo	54.5 ± 0.8	107.1 ± 0.9	357.0 ± 1.7	266.2 ± 10.9	0.8 ± 0.1
AL-09 seeds	24.1 ± 0.8	12.4 ± 0.2	497.4 ± 2.7	450.0 ± 14.3	1.0 ± 0.1
AL-103 seeds	37.6 ± 0.5	32.7 ± 0.6	285.8 ± 1.8	182.4 ± 6.1	1.1 ± 0.1
AL-12 seeds	47.3 ± 1.2	18.3 ± 0.9	213.2 ± 27.6	208.6 ± 3.7	1.0 ± 0.1
κI seeds	40.6 ± 0.6	14.1 ± 0.4	278.2 ± 2.4	221.8 ± 6.1	1.1 ± 0.1
AL-T05 seeds	23.3 ± 1.8	104.6 ± 5.2	179.8 ± 2.6	159.7 ± 46.6	1.2 ± 0.2

^aFrom ref 24.

^bFrom ref 27.

^cFrom ref 36.

^dFrom ref 31.