Skip to main content
. 2016 May 12;12(8):1215–1228. doi: 10.1080/15548627.2016.1179401

Figure 5.

Figure 5.

Modulation of the SN4741 cell viability by the CMA-PARK7 pathway. (A and B) The effect of modulating LAMP2A or PARK7 on MPP+-induced cellular apoptosis by TUNEL. SN4741 cells treated as in Fig. 4A or 4D were stained for TUNEL (mean ± SEM; n = 3). The numbers in the TUNEL panels indicate the ratio of TUNEL-positive cells/total cells. Scale bar: 100 μm. (C and D) The effect of modulating LAMP2A or PARK7 on MPP+-induced cell death by LDH release assay. SN4741 cells treated as described in (A and B) were assessed for cytotoxicity by LDH release assay (mean ± SEM; n = 3; *, P < 0.05; **, P < 0.01).