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. 2016 May 12;12(8):1240–1258. doi: 10.1080/15548627.2016.1179405

Figure 4.

Figure 4.

ChIP-seq analysis of TFE3 in LPS-stimulated RAW 264.7 cells. (A to C) GO analysis of the TFE3 binding sites. Numbers in parenthesis indicate the number of TFE3 targets. (A) Categories associated with “cellular compartment.” (B) Categories associated with “biological process.” (C) Categories associated with immune function. (D) Distribution of TFE3 binding sites in lysosomal, autophagy and endocytosis genes. Putative TFE3 binding sites tend to be concentrated within −1000 bp relative to the TSS. (E) Distribution of TFE3 binding sites in immune genes. Putative TFE3 binding sites were concentrated within −1500 bp or greater than −5000 bp relative to the TSS.