Figure 5.
DSS-induced colitis in Atg7 cKO mice. (A) Body weight was monitored during and after oral administration of 2.5% DSS for 5 d (n = 7 each). The antibiotic mixture (Abx) was administered since 2 d before DSS as described in Materials and Methods, and body weight monitored (n = 7 each). (B) Gross morphology (upper) and length (lower) of the colons on day 7 of DSS administration (n = 5 to 6). (C) Survival after administration of 4% DSS was monitored as described in Materials and Methods (n = 10 each). *, P < 0.05; **, P < 0.01.