Figure 8.

SESN2 is increased at the time when sepsis is exacerbated, and decreased at the time when sepsis is recovered. (A and B) Mice were injected with LPS (0, 24, 48, and 96 h, n = 9 per group). (A) Flow cytometry of SESN2 in mouse monocytes from blood stained with anti-SESN2-Alexa Flour 488 antibody and (B) serum IL1B and IL18 as measured by ELISA. Data shown are representative of 3 independent experiments and are the mean ± s .e.m. ***, p < 0.005 from an ANOVA followed by Tukey's post hoc test.