Table 1.
Patient, Tumor, and Treatment Characteristics for Internal and External Cohorts
| Variable | MSKCC (n = 3664) | % | External (n = 4551) | % | p-Value |
|---|---|---|---|---|---|
| Age at diagnosis | |||||
| <45 years | 1668 | 46% | 2203 | 48% | |
| ≥45 years | 1996 | 54% | 2348 | 52% | 0.009 |
| Sex | |||||
| Male | 995 | 27% | 1030 | 23% | |
| Female | 2669 | 73% | 3521 | 77% | <0.001 |
| Pathology | |||||
| Papillary carcinoma | 3436 | 94% | 4444 | 98% | |
| Follicular carcinoma | 129 | 4% | 70 | 2% | |
| Hürthle cell carcinoma | 99 | 3% | 37 | 1% | <0.001 |
| pT stage | |||||
| T1 | 1874 | 51% | 2361 | 52% | |
| T2 | 540 | 15% | 859 | 19% | |
| T3 | 1092 | 30% | 1047 | 23% | |
| T4 | 152 | 4% | 284 | 6% | |
| Unknown | 10 | 0% | – | – | <0.001 |
| pN stage | |||||
| N0Nx | 2556 | 70% | 2952 | 65% | |
| N1a | 548 | 15% | 793 | 17% | |
| N1b | 560 | 15% | 806 | 18% | <0.001 |
| M stage | |||||
| M0Mx | 3593 | 98% | 4403 | 97% | |
| M1 | 71 | 2% | 148 | 3% | <0.001 |
MSKCC, Memorial Sloan Kettering Cancer Center.