Table 4.
Continuous Age Variable: Factors Predictive of Disease-Specific Survival on Cox Proportional Hazards Model
| Variable | Unadjusted HR | 95% CI | p Value | Adjusted HR | 95% CI | p Value |
|---|---|---|---|---|---|---|
| Age at diagnosis (years)* | 1.114 | 1.09–1.14 | <0.001 | 1.076 | 1.06–1.1 | <0.001 |
| Sex | ||||||
| Female | reference | reference | ||||
| Male | 2.93 | 1.75–4.89 | <0.001 | 1.27 | 0.70–2.28 | 0.43 |
| Pathology | ||||||
| Papillary Ca | reference | reference | ||||
| Follicular Ca | 2.86 | 1.22–6.71 | 0.015 | 4.36 | 1.56–12.07 | 0.004 |
| Hürthle Cell Ca | 2.94 | 1.17–7.4 | 0.022 | 3.01 | 1.09–8.32 | 0.034 |
| pT stage | ||||||
| T1 | reference | reference | ||||
| T2 | 1.04 | 0.33–3.32 | 0.95 | 0.78 | 0.24–2.54 | 0.67 |
| T3 | 2.94 | 1.38–6.28 | 0.005 | 1.26 | 0.56–2.84 | 0.58 |
| T4 | 19.3 | 9.26–40.3 | <0.001 | 3.65 | 1.54–8.63 | 0.003 |
| pN stage | ||||||
| N0NX | reference | reference | ||||
| N1a | 1.48 | 0.68–3.2 | 0.325 | 1.85 | 0.75–4.55 | 0.18 |
| N1b | 3.6 | 2.0–6.3 | <0.001 | 2.01 | 0.91–4.45 | 0.08 |
| M stage | ||||||
| M0 | reference | reference | ||||
| M1 | 45.38 | 27.11–75.96 | <0.001 | 14.88 | 8.27–26.78 | <0.001 |
*
Age (continuous) adjusted for sex, pathology, and T, N, and M stage.