Table 1.
Experimental Values of Bilayer Thickness h and E Obtained from the Topography and Nanomechanical Measurement of the Lipid Domains and Estimated Values for KA and kC
Bilayer thickness |
Young’s modulus |
Stretch modulus |
Bending stiffness |
|
---|---|---|---|---|
h (nm) | E (MPa) | KA (pN/nm) | kC (kBT) | |
ld DOPC domain | 4.6 ± 0.2 | 33 ± 7 | 202.0 | 23.8 |
ld DOPC domain + fluvastatin | 4.5 ± 0.2 | 31 ± 14 | 183.4 | 21.3 |
ld DOPC domain + atorvastatin | 4.4 ± 0.2 | 36 ± 9 | 212.0 | 23.7 |
so DPPC domain | 5.5 ± 0.2 | 40 ± 10 | 289.2 | 48.9 |
so DPPC domain + fluvastatin | 5.4 ± 0.2 | 50 ± 30 | 355.9 | 58.5 |
so DPPC domain + atorvastatin | 5.7 ± 0.3 | 81 ± 37 | 615.6 | 114.1 |
Data are averaged from the means of the log-normal distributions of at least three different samples for each composition.