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. 2016 Jul 26;111(2):294–300. doi: 10.1016/j.bpj.2016.06.015

Figure 1.

Figure 1

Mode of Li+ binding to ATP·Mg. (A) Schematic representation of ATP with Mg2+ bound to the β and γ phosphates is shown. (B) Three possible modes of Li+ binding to ATP·Mg (phosphates, red; Mg2+, blue; Li+, green) are shown. Scheme 1 represents Lif + ATP·Mg → ATP·Mg + Lif. Scheme 2 represents Lif + ATP·Mg → ATP·Li + Mgf. Scheme 3 represents Lif + ATP·Mg → ATP·Mg·Li. (C) Representative 7Li T1 relaxation data in the absence (open circles) and presence (closed circles) of 50 μM MnCl2 in a sample of 10 mM ATP, 11 mM MgCl2, and 10 mM LiCl; smooth curves are single-exponential fits.