Figure 9.

Effect of aqueous flow suppressants measured by fluorophotometry. Mice were anesthetized with ketamine/xylazine. Timolol, or dorzolamide (CAI), was applied topically and fluorophotometry was performed 1 hour later. On a separate day, fluorophotometry was done in the same mice similarly anesthetized but without topical eye drop (Control). Treatment affected aqueous flow (Fa); by 1-way ANOVA encompassing all three treatments (P = 0.04). CAI treatment caused a decrease in Fa compared to control (*P = 0.03, by posthoc analysis).