. 2016 May 3;107(6):846–852. doi: 10.1111/cas.12929

Table 2.

Univariate and multivariate Cox regression analyses of potential prognostic factors for overall survival in patients with endometrial carcinoma (EC) (n = 79)

Clinicopathological feature	n	Univariate analysis P‐value		Multivariate analysis
Clinicopathological feature	n	Log‐rank	Wilcoxon	HR	95% CI	P‐value
Age (years)
<60	41	0.0393^a	0.0431^a	8.08	0.01‐0.12	<0.001^a
≥60	38
Stage
I	41	0.0016^a	0.0012^a	ND	ND	ND
II–IV	38
Grading
G1	27	0.0235^a	0.0229^a	4.46	1.59–14.42	0.0036^a
G2, 3	44
Depth of muscle invasion
<50%	46	0.1435	0.1185	ND	ND	ND
≥50%	28
Vascular invasion
Negative	40	0.2808	0.3001	ND	ND	ND
Positive	33
Lymph node metastasis
Negative	66	0.0028^a	0.0029^a	3.99	1.52–10.8	0.0054^a
Positive	13
Menstruation
Premenopausal	23	0.7004	0.6791	ND	ND	ND
Postmenopausal	56
CD169⁺ cells/mm² in RLNs
<350	40	0.0139^a	0.0098^a	ND	ND	ND
≥350	39
CD68⁺ cells/mm² in RLNs
<750	40	0.6403	0.5173	ND	ND	ND
≥750	39
CD169⁺ cells/CD68⁺ cells in RLNs
<0.7	41	0.0042^a	0.0029^a	1.29	0.72‐2.39	0.395
≥0.7	38
CD8⁺ cells/mm² in tumor
<120	36	0.0959	0.1098	ND	ND	ND
≥120	39
CD57⁺ cells/mm² in tumor
<50	38	0.0114^a	0.0177^a	0.32	0.11–0.83	0.018^a
≥50	37

Statistically significant results. CI, confidence interval; HR, hazard ratio; ND, not done.