Table I.
Differentially expressed proteins in the CML-T1/IR cells.
| Spot no. | Uniprot | Protein name | Fold change | P-value | Sequence coverage (%) | Mascot score | MW (Da) | pI |
|---|---|---|---|---|---|---|---|---|
| Upregulated | ||||||||
| 1 | O14745 | Na+/H+ exchange regulatory cofactor NHERF1 | 2.84 | <0.009 | 21 | 57 | 39,130 | 5.55 |
| 2 | O14745 | Na+/H+ exchange regulatory cofactor NHERF1 | >10 | <0.001 | 32 | 84 | 39,130 | 5.55 |
| 3 | Q9Y230 | RuvB-like 2 | 6.8 | <0.015 | 29 | 81 | 51,296 | 5.49 |
| 4 | P27797 | Calreticulin | 1.8 | <0.023 | 24 | 71 | 48,283 | 4.29 |
| 5 | P00813 | Adenosine deaminase | 2.9 | <0.009 | 36 | 87 | 41,024 | 5.63 |
| 6 | P67936 | Tropomyosin α-4 chain | 1.56 | <0.036 | 63 | 198 | 28,619 | 4.67 |
| 7 | P04792 | Heat shock protein β-1 | >10 | <0.001 | 35 | 136 | 22,826 | 5.98 |
| Downregulated | ||||||||
| 8 | Q9Y230 | RuvB-like 2 | −2.17 | <0.02 | 38 | 149 | 51,296 | 5.49 |
| 9 | Q99536 | Synaptic vesicle membrane protein VAT-1 homolog | −3.7 | <0.039 | 34 | 60 | 42,122 | 5.88 |
| 10 | Q15691 | Microtubule-associated protein RP/EB family member 1 | −1.86 | <0.005 | 53 | 89 | 30,151 | 5.02 |
| 11 | P04792 | Heat shock protein β-1 | −2.2 | <0.001 | 44 | 75 | 22,826 | 5.98 |
Included in the table are the proteins with an expression difference of at least 1.5-fold and a statistical significance of change P<0.05. MW, molecular weight; pI, isoelectric point.