Table 2. Small Angle X-ray parameters.
| Complexes | Rg, Å | Dmax, Å | χ |
|---|---|---|---|
| RXRα DBD-Ramp2 DR1 | 18.5 ± 0.7 | 67 ± 5 | 1.18 |
| RXRα LBD | 24.5 ± 0.5 | 80 ± 5 | 1.41 |
| RXRα NTD-DBD-Ramp2 DR1 | 43 ± 2 | 160 ± 20 | 1.50 |
| RXRα ΔNTD-Ramp2 DR1 | 36 ± 0.5 | 125 ± 7 | 1.08 |
| RXRα full-length | 41 ± 3 | 150 ± 20 | 0.90 |
| RXRα full-length-Ramp2 DR1 | 44 ± 2 | 160 ± 20 | 0.93 |
Rg, and Dmax, are the radius of gyration and maximum size, calculated from the scattering data. χ is the discrepancy between the experimental data and the predicted scattering curves. The predicted scattering curves were obtained from the appropriate crystal structures in case of RXR LBD and RXR DBD-Ramp2 DR1, from the rigid body model for RXR ΔNTD-Ramp2 DR1 and from EOM ensembles for the two constructs containing NTD.