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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Bone. 2013 Oct 18;58:108–113. doi: 10.1016/j.bone.2013.10.012

Table 3.

Bone geometry and volumetric mineral density of the tibial diaphysis in children with nephrotic syndrome in comparison to healthy controls (mean ± SD).

Nephrotic syndrome Healthy controls P value Adjusted p value
Model 1 Model 2
N 29 29
Total BMC (mg/mm) 264.4 ± 75.8 246.4 ± 70.6 0.35 0.033 0.28
Total vBMD (mg/cm3) 503.7 ± 85.7 551.9 ± 86.1 0.037 0.045 0.14
Total bone CSA (mm2) 534.9 ± 162.7 463.2 ± 155.5 0.09 0.014 0.13
Cortical vBMD (mg/cm3) 1025.6 ± 57.3 1016.0 ± 68.6 0.57 0.60 0.18
Periosteal circumference (mm) 81.1 ± 12.4 75.4 ± 12.1 0.082 0.010 0.099
Endosteal circumference (mm) 65.8 ± 13.3 57.5 ± 12.7 0.018 0.007 0.058
Cortical CSA (mm2) 176.8 ± 57.9 187.6 ± 51.2 0.46 0.22 0.18
Cortical thickness (mm) 2.4 ± 0.7 2.8 ± 0.7 0.032 0.018 0.060
Muscle CSA (cm2) 40.7 ± 1.4 38.1 ± 1.3 0.39 0.15 0.96
BMC:muscle CSA 6.2 ± 1.2 6.2 ± 1.3 0.92 0.34 0.26

Model 1: Adjusted for age, gender, ethnicity, tanner stage and height.

Model 2: Adjusted for age, gender, ethnicity, tanner stage, height and weight.