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. 2016 Jul 8;113(30):8526–8531. doi: 10.1073/pnas.1605063113

Fig. 3.

Fig. 3.

AAV under the short gfaABC1D or the hSyn promoter selectively targets astrocytes or neurons, respectively. dHC infection of AAV9-short gfaABC1D-eGFP (A–C) or AAVDJ-hSyn-eGFP (D–F) 2 wk after bilateral injection (A, D). Shown are representative images of rostral-to-caudal brain sections [bregma −2.4 to −4.4 mm (45)]. All images of whole dHC are composite tile scans. In AAV9-short gfaABC1D-eGFP–infected cells, eGFP expression colocalizes with immunostaining of GFAP (B) but not NeuN (C) in subregions CA1 and CA3 and the dentate gyrus (DG). In AAVDJ-hSyn-eGFP–infected cells, eGFP expression colocalizes with NeuN (E) but not GFAP (F) in subregions CA1 and CA3 and the dentate gyrus.