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Chemiluminescence detection of NO generation from different concentrations of PAPA NONOate at room temperature or at 37 °C (A and B). Platelet activation in the presence of different concentrations of PAPA NONOate (C), nitrite (D), or recombinant GbX (E). For the experiments in D, the concentration of RBCs corresponds to 15% Hct (∼3 mM Hb). For the experiments in E, the concentration of nitrite is 10 µM.
