Table S1.
Histological examination of mice
| Genotype | Age | Pancreas | Lung | Liver | Salivary | Heart |
| FoxP3-GFPcreKI/Y PD-1 WT | 38 | 0 | 0 | 0 | 0 | 0 |
| 38 | 0 | 0 | 0 | 0 | 0 | |
| 42 | 0 | 1 | 0 | 0 | 0 | |
| 47 | 0 | 0 | 0 | ND | ND | |
| 71 | 0 | 1 | 0 | 0 | 0 | |
| 71 | 0 | 1 | 0 | 0 | 0 | |
| 80 | 1 | 0 | 0 | 0 | 0 | |
| FoxP3- GFPcreKI/Y PD-1 KO | 38 | 1 | 1 | 0 | 0 | 0 |
| 38 | 4 | 0 | 1 | 0 | 0 | |
| 47 | 3 | 1 | 1 | ND | ND | |
| 42 | 4 | 1 | 1 | 0 | 0 | |
| 56 | 4 | 1 | 1 | 0 | 1 | |
| 71 | 3 | 1 | 1 | 0 | 1 | |
| 71 | 4 | 1 | 1 | 1 | 1 |
Table summarizes the score of inflammation of organs from male FoxP3-GFPcreKI/Y PD-1 WT or male FoxP3-GFPcreKI/Y PD-1 KO mice at the indicated age (days). Score 0, absence of lymphocytic infiltrates; score 1, mild infiltrates; score 2, moderate infiltrates; score 3, marked infiltrates; score 4, almost complete destruction of organs. ND, not done.