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. 2016 Jul 13;113(30):8484–8489. doi: 10.1073/pnas.1520964113

Fig. 4.

Fig. 4.

Analysis of amplification bias from high-depth WGS. (A) Lorenz curves depicting uniformity of coverage for the two samples with the lowest SD in reads per 1-Mb bin from each amplification method. (B) Coverage breadth as a function of sequencing depth for the sample with the lowest SD in reads per 1-kb bin from each method. (C) Mean power spectra of 1-kb binned read depth for all samples analyzed from each amplification method. (D) Power spectra of 1-kb binned read depth for the sample with the lowest SD in reads per bin from each method.