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Synthetic NATs accelerate skin healing in mice. (A and B) Time course (days) of wound closure in wild-type mice treated daily with topical applications of vehicle (open bars) or synthetic NAT(24:0) (A), NAT(20:0) (B), PEA (C), or anandamide (D) (%; filled bars). Data are expressed as mean ± SEM (n = 9). *P < 0.05; **P < 0.01; ***P < 0.001 (compared with vehicle or wild-type mice, two-tailed Student’s t test).
