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. 2016 Aug 1;11(8):e0158735. doi: 10.1371/journal.pone.0158735

Fig 6. Repetitive inhalant ODE exposure increased serum TRACP 5b levels in WT and TLR2 KO but not TLR4 KO animals.

Fig 6

WT, TLR2 KO, and TLR4 KO mice were i.n. treated with ODE daily or saline for 3 weeks whereupon animals were euthanized 5 hrs following final exposure. Levels of tartrate-resistant acid phosphatase 5b (TRACP 5b) were determined in serum. Bar graphs represent the mean with standard error bars shown (N = minimum of 6 mice/group from 3 independent studies). Statistical significance denoted by asterisks (*p<0.05) as compared to respective saline treatment group.