Fig 9. Effective reproduction number as a function of mixing and treatment uptake for low and high ratios of primary to chronic infectivity.

The solid lines are repeated from Fig 6A and correspond to the baseline value of the ratio h₁/h₂ = 26.04. The dashed lines were obtained for h₁/h₂ = 4.65 by shifting infectivity from primary to chronic infection while retaining a constant total infectivity. Elimination can be achieved for smaller values of treatment uptake percentage and in a wider range of mixing parameter if the infectivity of the primary phase is lower.