Table 6.

Ulcerogenic activity of synthesized prodrugs (4a–d) and flurbiprofen

Serial number	Compounds	Ulcer index (mean ± SEM)
Control group	CMC*	0.37±0.37
1	Flurbiprofen	3.07±0.63
2	4a	1.75±0.09
3	4b	1.34±0.06
4	4c	1.76±0.58
5	4d	0.56±0.15

Note: Values are expressed as mean ± SEM, (n=6) by unpaired t-test;

^*P<0.05 vs flurbiprofen.

Abbreviations: CMC, carboxymethyl cellulose; SEM, standard error of the mean.