Table II. Gene Counts by Carrier Proportion and Self-Reported Ethnicity.
Carrier Proportion (CP) | African American | European American | Japanese American | Latino | All |
---|---|---|---|---|---|
CP = 0 | 24 (32%) | 27 (36%) | 27 (36%) | 25 (34%) | 23 (31%) |
0 < CP ≤ 0.01 | 12 (16%) | 20 (27%) | 18 (24%) | 21 (28%) | 18 (24%) |
0.01 < CP ≤ 0.02 | 6 (8%) | 14 (19%) | 12 (16%) | 12 (16%) | 10 (14%) |
0.02 < CP ≤ 0.03 | 10 (14%) | 4 (5%) | 5 (7%) | 7 (9%) | 10 (14%) |
CP > 0.03 | 22 (30%) | 9 (12%) | 12 (16%) | 9 (12%) | 13 (18%) |
All CP | 74 (100%) | 74 (100%) | 74 (100%) | 74 (100%) | 74 (100%) |
We observed variants in 74 distinct SnpEff annotated genes. Carrier proportion (CP) is defined as the number of individuals of a given ancestry who carry ≥ 1 non-synonymous (NS) rare variant divided by the number of individuals of that ancestry. Table displays count and (percent) of genes according to carrier proportion for each self-reported ancestry. ‘All’ refers to study participants from all ancestries combined. There were no NS rare variants observed in any ancestry for 23 of the 74 genes.