Table 2.
Risk of Event Versus Probability of Achieving a Complete Cytogenetic Response According to Molecular Response at Specific Time Points32
| BCR-ABL1/ABL1 Transcript Ratio | Percentage Probability of Outcome According to Transcript Ratio at Specified Time Points (Median Months to Outcome) | |||||
|---|---|---|---|---|---|---|
| MMR (BCR-ABL1/ABL1 <0.05%) | Event | |||||
| 3 mo | 6 mo | 12 mo | 3 mo | 6 mo | 12 mo | |
| ≤0.1% | 100 (3) | 96 (6) | 97 (12) | 4 (13) | 1 (38) | 3 (40) |
| >0.1% to 1% | 84 (6) | 69 (12) | 61 (18) | 3 (46) | 7 (30) | 2 (48) |
| >1% to 10% | 53 (17) | 44 (18) | 20 (33) | 11 (21) | 9 (34) | 8 (47) |
| >10% | 33 (15) | 15 (18) | 7 (46) | 13 (47) | 23 (14) | 50 (19) |
MMR indicates major molecular response; mo, months.