Table 2. Chromosome bands most affected by spontaneous breakage only in exposed individuals two and six years after oil spill exposure.
Cytogenetic study six years after oil exposure (Present P6y study) | Cytogenetic study two years after oil exposure (Previous P2y study) | |
---|---|---|
Exposed individuals | 47 | 91 |
Total breakpoints identified by G-banding | 251 | 203 |
Statistical methods used | ||
Fragile site multinomial (FSM method) | 1q32, 5q31, 6p21.2, 7q22, 8p23, 9q22, 17p11.2, Xq22 | 2q21, 3q27, 5q31 |
Statistical method using relative length of chromosome bands | 1q22, 1q32, 2q13, 2q21, 2q23, 2q34, 2q35, 3q25, 3q27, 4p15.2, 5q31, 6p11.2, 6q21, 7q22, 7q32, 8p23, 8q21.2, 9p22, 9q22, 9q32, 12p12, 16p13.1, 17p11.2, 18p11.2, 19p13.2, Xq13, Xq22, Xq24 | 1p34.1, 2q21, 3q27, 4q33, 12q11, 13q11, 17p11.2, 18q11.2 |
Bold chromosome bands are present only in exposed individuals in two studies.