Table E1.
Summary of treatment of possible autoimmune and autoinflammatory manifestations
| Treatment | Response |
|---|---|
| Nephritic/nephrotic syndrome | |
| Steroids | Partial |
| Steroids + CyA | Remission, then relapse when CyA stopped |
| Steroids + anti-CD20 mAb | No |
| Steroids + CyA | Partial; infectious complications |
| Crohn disease | |
| Steroids + CyA | No |
| Steroids + CyA + IVIG | No |
| Steroids + CyA + infliximab | Partial, then relapse |
| Steroids + CyA + talidomide | No |
| Steroids + cyclophosphamide | No |
| Steroids + adalimumab | Yes |
| PG | |
| Steroids + dapsone + adalimumab | No |
| Steroids + dapsone + adalimumab + MTX | Partial |
| Steroids + dapsone + anakinra | Yes |
| Arthritis and vasculitis | |
| Steroids + CyA | Remission, then relapse |
| Steroids + CyA + infliximab | No |
| Steroids + dapsone + adalimumab + MTX | No |
| Steroids + dapsone + anakinra | Yes |
IVIG, Intravenous immunoglobulin; MTX, methotrexate.