Table 1.
Strain | Number of culture positive/total number
|
|||||||
---|---|---|---|---|---|---|---|---|
Inoculum dose | Lymph node | Skin | Heart | Spleen | Bladder | Joint | All sites | |
ML23 pBBE22luc (parent) | 103 | 4/4 | 4/4 | 4/4 | 4/4 | 4/4 | 4/4 | 24/24 |
105 | 4/4 | 4/4 | 4/4 | 4/4 | 4/4 | 4/4 | 24/24 | |
HZ001 pBBE22luc (Δbba33) | 103 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/24 |
105 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/24 | |
107 | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 | 0/18 | |
HZ001 pHZ300 (Δbba33/bba33 Comp) | 103 | 4/4 | 4/4 | 4/4 | 4/4 | 4/4 | 4/4 | 24/24 |
105 | 4/4 | 4/4 | 4/4 | 4/4 | 4/4 | 4/4 | 24/24 |