Table 1.
Comparison of urinary and psychosocial symptoms between OAB and controls
| OAB | Controls | p-value | |
|---|---|---|---|
| No. of subjects | 51 | 30 | |
| Age (mean ± SD) | 53.8 ± 11.9 | 54.2 ± 12.3 | 0.98 |
| Sex (% females) | 73% | 57% | 0.14 |
| Race (% white) | 43.1% | 63.3% | 0.08 |
| Age of diagnosis of OAB (mean ± SD) | 47.5 ± 15.2 | NA | |
| % with OAB symptoms less than one year? | 24% | NA | |
| Urinary symptoms: (mean ± SD) | |||
| No. of daytime void* (1-6,7-8,9-10,11-12,13 times or more) | 1.8 ± 1.3* | 0.2 ± 0.6* | <0.001 |
| No of nighttime void** | 2.6 ± 1.1 | 0.9 ± 0.7 | <0.001 |
| How often rush to bathroom to void?*** | 2.7 ± 0.9*** | 0.6 ± 0.7*** | <0.001 |
| How often does urine leak before getting to the bathroom?**** | 2.2 ± 0.9**** | 0.3 ± 0.5**** | <0.001 |
| Urologic questionnaires: (mean ± SD) | |||
| ICIQ-UI (urinary incontinence, 0-21) | 12.0 ± 4.9 | 1.4 ± 2.0 | <0.001 |
| ICIQ-OAB (overactive bladder, 0-16) | 9.3 ± 2.6 | 2.0 ± 1.5 | <0.001 |
| OAB-q symptom bother subscale (6-36) | 19.1 ± 6.6 | 2.2 ± 2.8 | <0.001 |
| OAB-q quality of life subscale (13-78) | 29.7 ± 16.9 | 2.0 ± 3.0 | <0.001 |
| UDI-6 (urogenital distress inventory, 0-24) | 12.6 ± 5.6 | 0.9 ± 1.4 | <0.001 |
| IIQ-7 (incontinence impact questionnaire, 0-28) | 8.8 ± 8.2 | 0.1 ± 0.4 | <0.001 |
| USS (urgency severity scale, 0-3) | 2.1 ± 0.7 | 0.5 ± 0.6 | <0.001 |
| Numeric rating scale of urgency (0-10) | 6.1 ± 2.6 | 0.4 ± 0.6 | <0.001 |
| Numeric rating scale of frequency (0-10) | 6.4 ± 2.6 | 0.6 ± 0.9 | <0.001 |
| Psychosocial measures: (mean ± SD) | |||
| Depression (HADS-D) | 5.3 ± 3.9 | 2.8 ± 3.9 | <0.001 |
| Anxiety (HADS-A) | 7.5 ± 4.5 | 3.3 ± 3.6 | <0.001 |
| Psychological stress level (PSS) | 17.3 ± 8.1 | 10.7 ± 8.5 | <0.001 |
| Exposure to childhood sexual trauma (CTES) | 29.4% | 6.7% | 0.022 |
| Sleep (PROMIS-8b) | 54.3 ± 10.3 | 43.8 ± 9.2 | <0.001 |
| Fatigue (PROMIS-7a) | 54.7 ± 9.6 | 46.0 ± 6.4 | <0.001 |
Based on the categories of response on the ICIQ-OAB questionnaire:
*
How many times do you urinate during the day? 0=1 to 6 times, 1=7 to 8 times 2=9 to 10 times, 3=11 to 12 times, 4=13 or more times.
**
During the night, how many times do you have to get up to urinate, on average? 0=none, 1=one time, 2=two times, 3=three times, 4=four or more times
***
Do you have to rush to the toilet to urinate? 0=never, 1=occasionally, 2=sometimes, 3=most of the time, 4=all of the time
****
Does urine leak before you can get to the toilet? 0=never, 1=occasionally, 2=sometimes, 3=most of the time, 4=all of the time