Table 3.
Fatty acid composition in bone marrow supernatant fluid (BMSF) and blood plasma from three groups, control, osteopenia and osteoporosis, based on bone mineral density.
| Control (n=10) | Osteopenia (n=10) | Osteoporosis (n=17) | ||||
|---|---|---|---|---|---|---|
| Fatty Acids | BMSF | Plasma | BMSF | Plasma | BMSF | Plasma |
| (mol%) | (mol%) | (mol%) | ||||
| Saturated | 46.2 ± 12.0 | 38.1 ± 6.5 | 42.1 ± 12.3 | 35.4 ± 4.5 | 41.3 ± 8.5 | 38.8 ± 5.6 |
| Monounsaturated | 29.7 ± 5.1 | 32.2 ± 6.8 | 30.1 ± 4.2 | 26.1 ± 4.6* | 32.3 ± 6.5 | 28.5 ± 4.5 |
| Polyunsaturated | 24.0 ± 13.4 | 29.7 ± 11.5 | 33.8 ± 9.2 | 38.5 ± 6.1 | 25.6 ± 11.6 | 32.7 ± 4.7* |
| Total unsaturated | 53.8 ± 12.0 | 61.9 ± 6.5 | 57.9 ± 12.3 | 64.6 ± 4.5 | 57.9 ± 8.8 | 61.2 ± 5.6 |
| ± | ||||||
| Palmitic acid (C16:0) | 34.8 ± 10.8 | 27.3 ± 5.1 | 31.3 ± 10.7 | 26.3 ± 5.0 | 31.5 ± 6.8 | 30.4 ± 3.7 |
| Palmitoleic acid (C16:1 n-7) | 2.0 ± 0.7 | 2.6 ± 1.4 | 1.9 ± 1.1 | 1.8 ± 0.7 | 2.1 ± 1.0 | 2.4 ± 1.0 |
| Stearic acid (C18:0) | 11.5 ± 2.0 | 10.9 ± 2.9 | 10.8 ± 2.5 | 9.1 ± 1.9 | 10.6 ± 4.3 | 9.3 ± 2.9 |
| Oleic acid (C18:1 n-9 cis) | 26.5 ± 4.8 | 28.1 ± 7.2 | 26.1 ± 4.3 | 23.1 ± 4.3 | 28.5 ± 6.1 | 24.5 ± 3.6* |
| Elaidic acid (C18:1 n-9 trans) | 1.3 ± 0.8 | 1.5 ± 0.4 | 1.2 ± 0.8 | 1.2 ± 0.5 | 1.7 ± 0.8 | 1.6 ± 0.8 |
| Linoleic acid (C18:2 n-6) | 22.0 ± 9.2 | 25.3 ± 8.5 | 22.6 ± 11.2 | 31.9 ± 5.7* | 23.1 ± 10.0 | 29.2 ± 4.1* |
| Eicosatrienoic acid (C20:3 n- | 0.8 ± 0.7 | 0.9 ± 1.0 | 0.9 ± 0.6 | 1.3 ± 0.5 | 0.4 ± 0.6 | 0.9 ± 0.8 |
| Arachidonic acid (C20:4 n-6) | 3.3 ± 2.5 | 3.5 ± 3.0 | 4.3 ± 4.3 | 5.3 ± 1.4 | 2.0 ± 2.0 | 2.6 ± 1.9 |
The fatty acid analysis was performed in BMSF and blood plasma from donors classified according their bone mineral density. The Osteoporosis group includes donors with and without fractures. Results are expressed as mean ± standard deviation.
*
p<0.05 between BMSF and blood plasma.