Table 4.
Composition of fatty acid in bone marrow fluid from osteoporotic donors with and without hip fracture.
| Blood Plasma | Bone Marrow Supernatant Fluid | |||
|---|---|---|---|---|
| Fatty Acids |
Without fracture
(n=8) |
With fracture
(n=9) |
Without fracture
(n=8) |
With fracture
(n=9) |
| (mol%) | (mol%) | |||
| Saturated | 37.6 ± 4.6a,b | 40.0 ± 6.5 | 45.6 ± 8.5 | 37.0 ± 6.3* |
| Monounsaturated | 29.5 ± 3.2 | 27.4 ± 5.5c | 28.8 ± 5.3 | 34.1 ± 6.3* |
| Polyunsaturated | 32.8 ± 4.3 | 32.6 ± 5.2 | 24.1 ± 13.9 | 26.9 ± 9.8 |
| Total Unsaturated | 62.4 ± 4.6 | 60.0 ± 6.5 | 54.4 ± 8.5 | 63.0 ± 6.3 |
| Palmitic acid (C16:0) | 29.0 ± 3.7b | 32.2 ± 3.2 | 32.4 ± 7.7 | 30.7 ± 6.2 |
| Palmitoleic acid (C16:1 n-7) | 2.7 ± 0.9 | 2.0 ± 1.0 | 2.0 ± 1.0 | 2.3 ± 1.0 |
| Stearic acid (C18:0) | 9.4 ± 1.3a | 9.2 ± 4.0 | 13.2 ± 4.5 | 8.3 ± 2.7* |
| Oleic acid (C18:1 n-9 cis) | 25.1 ± 3.5 | 24.0 ± 3.7c | 24.9 ± 5.0 | 30.2 ± 5.3* |
| Elaidic acid (C18:1 n-9 trans) | 1.8 ± 0.5 | 1.4 ± 1.0 | 1.8 ± 0.8 | 1.6 ± 0.9 |
| Linoleic acid (C18:2 n-6) | 28.5 ± 3.5a | 30.0 ± 4.7 | 20.4 ± 10.9 | 25.6 ± 9.0 |
| Eicosatrienoic acid (C20:3 n-6) | 1.1 ± 0.8 | 0.6 ± 0.7c | 0.8 ± 0.7 | 0.1 ± 0.1* |
| Arachidonic acid (C20:4 n-6) | 3.2 ± 2.3 | 2.0 ± 1.3 | 4.6 ± 1.0 | 1.5 ± 0.8*** |
The Osteoporosis group was divided according the existence or not of hip fracture and each new group was analyzed independently. Results are expressed as mean ± standard deviation.
a
p<0.05; Plasma/without fracture vs BMSF/without fracture;
b
p<0.05; Plasma/without vs Plasma/with fracture;
c
p<0.05; Plasma/with vs BMSF/with fracture;
*
p < 0.05;
***
p<0.001; BMSF/without vs BMSF/with fracture.