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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Neurochem Int. 2016 Jun 6;98:129–137. doi: 10.1016/j.neuint.2016.05.010

Fig. 1. SERTCortexΔ eliminates SERT expression in PFC but not in thalamic and raphe neurons.

Fig. 1

A. qPCR analysis of SERT mRNA in brainstem, thalamic VB nuclei and PFC from SERTCortexΔ and control SERTfl/fl littermate mice. P5 mice were analyzed, with 4–5 animals/genotype (mean ± SEM, ***, p < 0.001, Student’s t-test). NS, not statistically significantly different. B. qPCR analysis of SERT mRNA in brainstem and thalamic VB nuclei from WT, SERTNull, SERTGluΔ, SERTRapheΔ and control SERTfl/fl littermate mice. This graph is reproduced from our previous study (Chen et al., 2015) to facilitate comparison here of the efficiency and selectivity of neuron-specific Cre-mediated SERT knockouts.