FIGURE 3.

Effect of OTA on hydroperoxide levels in Neuro-2a and its scavenging by NAC. (A) Neuro-2a cells were treated with various concentrations of OTA (100–500 nM) for 24 h. Hydroperoxide levels were quantified (B). Neuro-2a cells were pretreated with NAC (1 mM) for 24 h followed by OTA (500 nM) treatment for 24 h and amount of hydroperoxide produced was assessed. The data represented as mean ± SEM of three independent experiments. ^∗p < 0.05 versus respective control group and ^#p < 0.05 versus respective OTA treated group.