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A representative schematic of the structure of soluble TLR2 (sTLR2). sTLR2 comprises the extracellular portion of TLR2 and does not contain the transmembrane nor the TIR domains required for TLR2 signaling. The size of sTLR2 varies in different mucosal fluids, and is composed of cleaved portions of the N and C terminus.
