Table 3.

Mean change in DAS28

Duration	Single therapy N = 262	Interrupted therapy N = 142	Switched therapy N = 159
Mean difference in DAS28 from pre-treatment to ≥90 days after first course (95% CI)	−0.9 (−1.2, −0.7)	−1.1 (−1.5, −0.6)	−0.8 (−1.2, −0.4)
Mean difference in DAS28 during initial course to ≥90 days after second course (95% CI)	NA	−0.3 (−0.6, 0.0)	−0.2 (−0.5, 0.2)

DAS28 Disease activity score based on 28 joints, TNFi tumor necrosis factor inhibitor, CI confidence interval, NA not applicable