Table 1.
GABA− | GABA+ | Statistics | |
---|---|---|---|
RMP, mV | −52.5 (1.36) (n = 33) | −52.6 (1.16) (n = 38) | NS |
MR, MΩ | 589.3 (66.28) (n = 20) | 649.5 (73.33) (n = 20) | NS |
CAP, pF | 33.2 (3.48) (n = 20) | 25.8 (1.86) (n = 20) | P = 0.07 |
Threshold, nA | 0.031 (0.004) (n = 16) | 0.019 (0.003) (n = 20) | P = 0.027 |
Max firing, Hz | 12.3 (0.969) (n = 16) | 11.8 (1.8) (n = 20) | NS |
Breakpoint, nA | 0.14 (0.014) (n = 16) | 0.09 (0.016) (n = 20) | P = 0.047 |
IA | 52% (17/33) | 31% (11/35) | P = 0.09 |
Ih | 15% (4/27) | 38% (12/32) | P = 0.05 |
PIR | 43% (13/30) | 43% (17/40) | NS |
Burst | 24% (7/29) | 50% (17/34) | P = 0.035 |
Tonic | 76%(22/29) | 50% (17/34) |
Parameter values are means (SE).
RMP, resting membrane potential; MR, membrane resistance; CAP, capacitance; PIR, postinhibitory rebound; NS, not significant.