Table 2.

Microarray results and description of genes selected for further analysis

				Microarray results
				Persistently HPV16-infected versus HPV-negative women
Gene symbol	Chromosome	Gene description	Gene ontology	T-test (p-value)	Ratio of means1
TMEM45A	3q12.2	Transmembrane protein 45A	Integral to membrane	< 0.0001	3.63
TNFAIP6	2q23.2	Tumor necrosis factor, alpha-induced protein 6	Inflammatory response, cell adhesion, signal transduction, cell-cell signaling	< 0.0001	0.05
CD44	11p13	CD44 antigen (homing function and Indian blood group system)	Regulation of cell growth, inflammatory response, cell adhesion, cell migration	< 0.0001	0.14
CCRL2	3p21	Chemokine (C-C motif) receptor-like 2	Chemotaxis, signal transduction, receptor activity	< 0.00001	0.04
p16INK4a2	9p21	Cyclin-dependent kinase inhibitor 2A	Cell cycle checkpoint, regulation of cyclin-dependent protein kinase activity, G1/S transition of mitotic cell cycle, DNA fragmentation involved in apoptosis, transcription	0.5193	0.93
SERPINB52	18q21.3	Serpin peptidase inhibitor, clade B (ovalbumin), member 5	Cell motion, serine-type endopeptidase inhibitor activity, protein binding	0.0144	2.69

¹Ratio of means was computed as “mean expression value in persistently HPV16-infected women”/“mean expression value in HPV-negative women”;

²Included in analysis based on à priori hypotheses.